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Invitrogen
UBA1 Recombinant Rabbit Monoclonal Antibody (WN14)
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产品信息
MA573812
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
WN14
抗原
Recombinant Human UBA1 aa 626-889.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1) encodes a key E1 enzyme that initiates the ubiquitin-proteasome system, which controls protein degradation and turnover in cells. UBA1 activates ubiquitin in an ATP-dependent manner and transfers it to E2 conjugating enzymes, enabling the tagging of target proteins for degradation or other regulatory processes. It is essential for cell viability and has been implicated in disorders such as X-linked spinal muscular atrophy and VEXAS syndrome when mutated.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A1S9T and BN75 temperature sensitivity complementing; POC20 centriolar protein homolog; Protein A1S9; testicular secretory protein Li 63; UBA1, ubiquitin-activating enzyme E1 homolog A; Ubiquitin-activating enzyme E1; Ubiquitin-like modifier-activating enzyme 1; unnamed protein product
基因别名: A1S9; A1S9T; A1ST; AMCX1; CFAP124; GXP1; POC20; SMAX2; UBA1; UBA1A; UBE1; UBE1X; VEXAS
UniProt ID: (Human) P22314
Entrez Gene ID: (Human) 7317
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