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Invitrogen
UBE2D2 Polyclonal Antibody
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产品信息
PA5-86740
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide, corresponding to amino acids 102-147 of Human UBE2D2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: (E3-independent) E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2; E2(17)KB 2; p53-regulated ubiquitin-conjugating enzyme 1; ubc2e ubiquitin conjugating enzyme; Ubiquitin carrier protein D2; ubiquitin conjugating enzyme 2e; ubiquitin conjugating enzyme E2D 2; Ubiquitin-conjugating enzyme E2 D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Ubiquitin-protein ligase D2
基因别名: 1500034D03Rik; E2(17)KB2; E217kB; PUBC1; Ubc2e; UBC4; UBC4/5; UBC5B; UBCH4; UBCH5B; UBE2D2; Ube2d2a
UniProt ID: (Human) P62837, (Mouse) P62838
Entrez Gene ID: (Human) 7322, (Rat) 641452, (Mouse) 56550
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
cellular protein modification process
ubiquitin-dependent protein catabolic process
protein ubiquitination
TRIF-dependent toll-like receptor signaling pathway
Fc-epsilon receptor signaling pathway
T cell receptor signaling pathway
protein autoubiquitination
regulation of transcription from RNA polymerase II promoter in response to hypoxia
protein K48-linked ubiquitination
metabolic process
