Search Thermo Fisher Scientific
图: 1 / 1
Immunogen sequence: MSSPSPGKRR MDTDVVKLIE SKHEVTILGG LNEFVVKFYG PQGTPYEGGV WKVRVDLPDK YPFKSPSIGF MNKIFHPNID EASGTVCLDV INQTWTALYD LTNIFESFLP QLLAYPNPID PLNGDAAAMY LHRPEEYKQK IKEYIQKYAT EEALKEQEEG TGDSSSESSM SDFSEDEAQD MEL; Positive Samples: SW480, BT-474, 293T, U-251MG, SKOV3, Mouse thymus, Mouse liver, Mouse lung, Rat lung
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: (E3-independent) E2 ubiquitin-conjugating enzyme H; E2 ubiquitin-conjugating enzyme H; GID complex subunit 3, UBC8 homolog; UBCH2; Ubiquitin carrier protein H; ubiquitin conjugating enzyme E2H; Ubiquitin-conjugating enzyme E2 H; Ubiquitin-conjugating enzyme E2-20K; ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8); ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); Ubiquitin-protein ligase H
基因别名: 1500009C23Rik; AI181839; AI326965; AI462483; AW227540; E2-20K; GID3; N28148; UBC8; UBCH; UBCH2; UBE2H
UniProt ID: (Human) P62256, (Mouse) P62257
Entrez Gene ID: (Human) 7328, (Rat) 296956, (Mouse) 22214
分子生物学功能: ubiquitin-protein ligase