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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: ERSTVARIQF RLPDGSSFTN QFPSDAPLEE ARQFAAQTVG NTYGNFSLAT MFPRREFTKE DYKKKLLDLE LAPSASVVLL PAGRPTASIV
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its ocogenic activity. Serves as an ocogene or tumor supressor depending on the cell context.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Erasin; UBX domain containing 2; UBX domain-containing protein 2; UBX domain-containing protein 4
基因别名: 1300013G12Rik; KIAA0242; mKIAA0242; UBXD2; UBXDC1; UBXN4
UniProt ID: (Rat) Q5HZY0, (Mouse) Q8VCH8
Entrez Gene ID: (Rat) 304766, (Mouse) 67812