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Invitrogen
UCP3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-76064
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human UCP3.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: mitochondrial uncoupling protein 3; similar to uncoupling protein; solute carrier family 25 member 9; uncoupling protein; uncoupling protein 3 (mitochondrial proton carrier) isoform UCP3_1; uncoupling protein 3 (mitochondrial proton carrier) isoform UCP3_2; uncoupling protein 3 (mitochondrial, proton carrier); unnamed protein product
基因别名: SLC25A9; UCP-3
UniProt ID: (Human) P55916, (Mouse) P56501
Entrez Gene ID: (Human) 7352, (Mouse) 22229
response to superoxide
response to hypoxia
fatty acid metabolic process
lipid transport
response to nutrient
response to cold
response to activity
response to insulin
cellular response to hormone stimulus
response to steroid hormone
response to glucocorticoid
transmembrane transport
positive regulation of cold-induced thermogenesis
lipid hydroperoxide transport
response to fenofibrate
hydrogen ion transmembrane transport
mitochondrial transmembrane transport
adaptive thermogenesis
lipid metabolic process
respiratory gaseous exchange
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
