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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: WLSMKDIVEV LSDRGHEIVV VVPEVNLLLK ESKYYTRKIY PVPYDQEELK NRYQSFGNNH FAERSFLTAP QTEYRNNMIV IGLY
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 73%.
UGT1A6 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC29860; Phenol-metabolizing UDP-glucuronosyltransferase; UDP glucuronosyltransferase 1 family, polypeptide A6; UDP glycosyltransferase 1 family, polypeptide A6; UDP-glucuronosyltransferase 1 family polypeptide A6s; UDP-glucuronosyltransferase 1-6; UDP-glucuronosyltransferase 1-F; UDP-glucuronosyltransferase 1A6; UDPGT 1-6; UGT-1F; UGT1*6; UGT1-06; UGT1.6
基因别名: GNT1; HLUGP; HLUGP1; UDPGT; UDPGT 1-6; UGT1; UGT1A6; UGT1A6S; UGT1F
UniProt ID: (Human) P19224
Entrez Gene ID: (Human) 54578