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Predicted to react with rat based on sequence homology.
UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase 8A; UDP-glucuronosyltransferase 8; uridine diphosphate glycosyltransferase 8
基因别名: AI850488; AW455908; CGT; mCerGT; UGT4; UGT8; Ugt8a
UniProt ID: (Human) Q16880, (Mouse) Q64676
Entrez Gene ID: (Human) 7368, (Mouse) 22239