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Invitrogen
ULBP3 Recombinant Rabbit Monoclonal Antibody (R4P1-B1)
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ULBP3 Antibody (705197R) in WB
Western blot was performed using ULBP3 Recombinant Rabbit Monoclonal Antibody (R4P1-B1) (Product # 705197R) and ~20 kDa band corresponding to ULBP3 was observed in SW620, HeLa and K-562 cell lines as compared to A549 and MCF7 cell lines which are reported to be negative for ULBP3 expression. Membrane-enriched extracts (30 µg lysate) of SW620 (Lane 1), HeLa (Lane 2), K-562 (Lane 3), A549 (Lane 4) and MCF7 (Lane 5) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred ont... View More
产品信息
705197R
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
R4P1-B1
抗原
Protein corresponding to human ULBP3 [aa30 -aa217]
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Recombinant Rabbit monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
靶标信息
UL16-binding protein 3 (ULBP3) is an extended member of the MHC class I superfamily. It does not contain the alpha 3 domain and lacks a transmembrane domain. ULBP3 binds and activates the KLRK1/NKG2D receptor and mediates natural killer cell cytotoxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ALCAN-gamma; N2DL-3; NKG2D ligand 3; NKG2D ligand3; Retinoic acid early transcript 1N; UL16-binding protein 3; ULBP; ULBP 3; unnamed protein product
基因别名: N2DL-3; N2DL3; NKG2DL3; RAET1N; ULBP3
UniProt ID: (Human) Q9BZM4
Entrez Gene ID: (Human) 79465
positive regulation of T cell mediated cytotoxicity
immune system process
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
immune response
natural killer cell activation
natural killer cell mediated cytotoxicity
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