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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: ATLLSHPQQR PPFLRQAIKI RRRRVRDLQD PPPQMAPEIQ PPSHHFSPEQ RALLYEDALY TVLHRLGHPE PNHVTEASEL LRYLQEAFHV EPEEHQQTL
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: likely ortholog of H. sapiens unc-13 homolog D (UNC13D); munc 13-4; Munc13-4; Protein unc-13 homolog D
基因别名: 2610108D09Rik; Jinx; mFLJ00067; Munc13-4; UNC13D
UniProt ID: (Mouse) B2RUP2
Entrez Gene ID: (Mouse) 70450