Invitrogen

UNC93B1 Polyclonal Antibody

Name: UNC93B1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-23196
Availability: InStock

查看其他7个UNC93B1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

图: 1 / 1

UNC93B1 Antibody (PA5-23196) in WB

Western blot analysis of UNC93B1 in human spleen lysate in the 1) absence and 2) presence of immunizing peptide, and 3) mouse spleen lysate. Samples were incubated in UNC93B1 polyclonal antibody (Product # PA5-23196).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image UNC93B1 Polyclonal Antibody

产品信息

PA5-23196

应用

建议稀释比

已发表文章

免疫印迹 (WB)

3-5 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A portion of amino acid 500-550 of mouse UNC93B protein.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.0 mg/mL

100 µg

纯化类型

Protein G

保存液

PBS

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2540722

靶标信息

The endoplasmic reticulum (ER) protein Unc93b, a human homolog of the C. elegans Unc93 gene, was initially identified by a forward genetic screen using N-ethyl-N-nitrosourea where a histidine-to-arginine substitution in Unc93b caused defects in Toll-like receptor (TLR) 3, 7 and 9 signaling. Unlike Unc93a, another homolog of the C. elegans Unc93 gene whose function is unknown, Unc93b specifically interacts with TLR3, 7 and 9; the histidine-to-arginine point mutation used to identify Unc93b abolishes this interaction. Mice carrying this point mutation are highly susceptible to infection with a number of viruses, indicating that Unc93b plays an important role in innate immunity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。