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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: IYKSTKCNDM QQSGSCPRGP FCAFAHVEQP PLSDDLQPSS AVSSPTQPGP VLYMPSAAGD SVPVSPSSPH APDLSALLCR NSSLGSPSNL CGSPPGSIRK PPNLEGIVFP GES
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 86%.
Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RING finger protein unkempt homolog; Zinc finger CCCH domain-containing protein 5
基因别名: KIAA1753; UNK; ZC3H5; ZC3HDC5
Entrez Gene ID: (Human) 85451