Invitrogen

UPB1 Polyclonal Antibody

Name: UPB1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-51450

高级验证

查看其他6个UPB1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (4)
高级验证 (1)

UPB1 Antibody in Immunohistochemistry (IHC)

图: 1 / 5

UPB1 Antibody (PA5-51450) in IHC

Immunohistochemical staining of UPB1 in human liver and colon tissues using UPB1 Polyclonal Antibody (Product # PA5-51450). Corresponding UPB1 RNA-seq data are presented for the same tissues.

Product Image Gallery

UPB1 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of UPB1 demonstrates antibody specificity. Immunohistochemical analysis of UPB1 using anti-UPB1 Polyclonal Antibody (Product # PA5-51450), shows significant staining of UPB1 in human liver and shows minimal or weak staining in human colon tissues. The relative expression levels of UPB1 within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image UPB1 Polyclonal Antibody

产品信息

PA5-51450

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human UPB1. Recombinant protein control fragment (Product #RP-91381).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2649283

产品详细信息

Immunogen sequence: GALSESLWPI EARNAAIANH CFTCAINRVG TEHFPNEFTS GDGKKAHQDF GYFYGSSYVA APDSSRTPGL SRSRDGLLVA KLDLNLCQQV NDVWNFKMTG RYEMYARELA EAVKSNYS

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.

靶标信息

UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。