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Invitrogen
USH1C Polyclonal Antibody
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图: 1 / 7
USH1C Antibody (PA5-115341) in ICC/IF
Immunocytochemistry analysis of USH1C in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115341). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115341
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human USH1C(Accession Q9Y6N9), corresponding to amino acid residues Q406-L456.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Harmonin.
靶标信息
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alternatively spliced; scaffold protein with pdz domains; antigen NY-CO-38/NY-CO-37; autoimmune enteropathy-related antigen AIE-75; harmonin a1; PDZ domain protein; PDZ domain-containing protein; PDZ-73 protein; renal carcinoma antigen NY-REN-3; unnamed protein product; Usher syndrome 1C (autosomal recessive severe) isoform USH1C_1; Usher syndrome 1C (autosomal recessive severe) isoform USH1C_2; Usher syndrome 1C (autosomal recessive, severe); Usher syndrome 1C homolog; usher syndrome type-1C protein; usher syndrome type-1C protein homolog
基因别名: 2010016F01Rik; AIE-75; DFNB18; DFNB18A; harmonin; NY-CO-37; NY-CO-38; PDZ-45; PDZ-73; PDZ-73/NY-CO-38; PDZ73; PDZD7C; ush1cpst
UniProt ID: (Human) Q9Y6N9, (Mouse) Q9ES64
Entrez Gene ID: (Human) 10083, (Rat) 308596, (Mouse) 72088
G2/M transition of mitotic cell cycle
auditory receptor cell morphogenesis
sensory perception of sound
parallel actin filament bundle assembly
regulation of microvillus length
inner ear morphogenesis
auditory receptor cell differentiation
photoreceptor cell maintenance
retinal cone cell development
neuromuscular process controlling balance
sensory perception of light stimulus
equilibrioception
actin filament bundle assembly
inner ear receptor stereocilium organization
protein-containing complex assembly
protein localization to microvillus
brush border assembly
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