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Invitrogen
USP12 Polyclonal Antibody
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产品信息
PA5-139844
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: RLPNGNIDNE NNNSTPDPTW VHEI
Highest antigen sequence indentity to the following orthologs: Mouse - 83%, Rat - 79%.
靶标信息
Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Deubiquitinating enzyme 12; Ubiquitin carboxyl-terminal hydrolase 12; Ubiquitin specific peptidase 12; ubiquitin specific protease 12 like 1; Ubiquitin thioesterase 12; ubiquitin thiolesterase 12; Ubiquitin-hydrolyzing enzyme 1; Ubiquitin-specific-processing protease 12
基因别名: UBH1; USP12; USP12L1
UniProt ID: (Human) O75317
Entrez Gene ID: (Human) 219333
