Invitrogen

Ubinuclein 1/2 Polyclonal Antibody

Name: Ubinuclein 1\/2 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-37942

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

Ubinuclein 1/2 Antibody in Western Blot (WB)

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Ubinuclein 1/2 Antibody (PA5-37942) in WB

Western blot analysis of Ubinuclein 1/2 using Ubinuclein 1/2 Polyclonal Antibody (Product # PA5-37942) (1 µg/mL) in staining of MOLT4 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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Immunogen image

Immunogen Image Ubinuclein 1/2 Polyclonal Antibody

产品信息

PA5-37942

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-3 µg/mL

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide with sequence C-DNSEAYDELVPASLT, from the internal region of UBN1

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2554548

产品详细信息

This antibody is predicted to react with mouse, rat, dog, pig, cow and zebrafish based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

靶标信息

Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.

仅用于科研。不用于诊断过程。未经明确授权不得转售。