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NeoBiotechnologies
Uroplakin 1B (Urothelial Differentiation Marker) Monoclonal Antibody (MSVA-734M)
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产品信息
7348-MSM15-P1
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
MSVA-734M
抗原
Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary).
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product cellular localization: Cytoplasm, Endoplasmic reticulum membrane.
Positive control: Pancreas: Islets cells and interspersed nerve fibres should show strong PGP9.5 staining.
Tissue specificity: Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.
靶标信息
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: tetraspan; Tetraspanin-20; Tspan-20; UP1b; UPIb; Uroplakin Ib; Uroplakin-1b
基因别名: TSPAN20; UPIB; UPK1; UPK1B
UniProt ID: (Human) O75841
Entrez Gene ID: (Human) 7348
