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产品信息
PA5-54793
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2649409
产品详细信息
Immunogen sequence: PQVLAVAAHD VGEYVRHYPR GKRVIEQLGG KQLVMNHMHH EDQQVRYNAL LAVQKLMVHN WEYLGKQLQS E
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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生物信息学
蛋白别名: ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H; NBP1; Nef-binding protein 1; Protein VMA13 homolog; V-ATPase 50/57 kDa subunits; V-ATPase subunit H; V-type proton ATPase subunit H; vacuolar ATP synthase subunit H; vacuolar ATPase subunit H; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD
基因别名: ATP6V1H; CGI-11; MSTP042; NBP1; SFD; SFDalpha; SFDbeta; VMA13
UniProt ID: (Human) Q9UI12
Entrez Gene ID: (Human) 51606
endocytosis
vacuolar acidification
insulin receptor signaling pathway
ATP hydrolysis coupled proton transport
viral process
regulation of macroautophagy
transferrin transport
ion transmembrane transport
regulation of defense response to virus by virus
regulation of catalytic activity
phagosome acidification
