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Invitrogen
VAPB Recombinant Rabbit Monoclonal Antibody (208)
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VAPB Antibody (MA5-29639) in WB
Western Blot using VAPB Recombinant Rabbit Monoclonal Antibody (208) (Product # MA5-29639) at 1:500 dilution. Lane A: HepG2 Whole Cell Lysate, Lane B: A549 Whole Cell Lysate, Lane C: Jurkat Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 27 kDa. Observed band size: 32 kDa.
产品信息
MA5-29639
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
208
抗原
Recombinant Human VAPB/VAP-B protein (Met1-Pro132)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human VAPB/VAP-B.
靶标信息
Vesicle-associated membrane protein-associated protein B/C is a protein that in humans is encoded by the VAPB gene. The VAPB gene is found on the 20th human chromosome. The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ALS 8; ALS8VAMP-B/VAMP-C; vamp; VAMP (vesicle-associated membrane protein)-associated protein B and C; Vamp 33b; VAMP B; VAMP B VAMP C; VAMP B/VAMP C; VAMP C; VAMP-associated 33 kDa protein; VAMP-B/VAMP-C; VAMP-C; VAMPB; VAMPB/VAMPC; VAMPC; VAP 33b; VAP B; VAP B/VAP C; VAP C; VAP-B/VAP-C; VAP-C; VAPB/VAPC; VAPC; Vesicle-associated membrane protein-associated protein B/C
基因别名: ALS8; UNQ484/PRO983; VAMP-B; VAP-B; VAPB
UniProt ID: (Human) O95292
Entrez Gene ID: (Human) 9217
cellular calcium ion homeostasis
ER to Golgi vesicle-mediated transport
activation of signaling protein activity involved in unfolded protein response
endoplasmic reticulum organization
modulation by virus of host morphology or physiology
sphingolipid biosynthetic process
endoplasmic reticulum unfolded protein response
positive regulation of viral genome replication
COPII-coated vesicle budding
cell-cell adhesion
