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Invitrogen
VAPB Monoclonal Antibody (699811)
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VAPB Antibody (MA5-24318) in IHC (F)
Immunohistochemical analysis of VAPB in perfusion fixed frozen sections of rat brain (medulla). Samples were incubated with VAPB monoclonal antibody (Product # MA5-24318) using a dilution of 8 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to gigantocellular neurons.
产品信息
MA5-24318
产品规格
种属反应
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
699811
抗原
E. coli-derived recombinant rat VAP-B Ala2-Pro132
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
靶标信息
Vesicle-associated membrane protein-associated protein B/C is a protein that in humans is encoded by the VAPB gene. The VAPB gene is found on the 20th human chromosome. The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ALS 8; ALS8VAMP-B/VAMP-C; vamp; Vamp 33b; VAMP B; VAMP B VAMP C; VAMP B/VAMP C; VAMP C; VAMP-associated protein B; VAMP-B; VAMP-C; VAMPB; VAMPB/VAMPC; VAMPC; VAP 33b; VAP B; VAP B/VAP C; VAP C; VAP-B; VAP-B/VAP-C; VAP-C; VAPB/VAPC; VAPC; vesicle-associated membrane protein, associated protein B and C; Vesicle-associated membrane protein-associated protein B
基因别名: Vapb
UniProt ID: (Rat) Q9Z269
Entrez Gene ID: (Rat) 60431
cellular calcium ion homeostasis
ER to Golgi vesicle-mediated transport
activation of signaling protein activity involved in unfolded protein response
endoplasmic reticulum organization
biological_process
modulation by virus of host morphology or physiology
endoplasmic reticulum unfolded protein response
negative regulation by host of viral release from host cell
positive regulation by host of viral release from host cell
negative regulation by host of viral genome replication
positive regulation by host of viral genome replication
positive regulation of viral genome replication
negative regulation by virus of viral protein levels in host cell
COPII-coated vesicle budding
