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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: DTLESSLEDP LRSFVRVLEK RDGTVLRLQQ YSSGGVGCVV WDAAIVLSKY LETPEFSGDG AHALSRRSVL ELGSGTGAVG LMAATLGADV VVTDLEELQD LLKMNINMNK HLVTGSVQAK GGRNRRLSFS TRLHTDGRLH I
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 29%.
C14orf138, also named as VCPKMT or METTL21D, is 229 amino acid protein, which belongs to the methyltransferase superfamily. C14orf138 localizes in the cytoplasm and interacts with ALKBH6. C14orf138 as a Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. C14orf138 exists as five isoforms. The calculated molecular weight of C14orf138 is 26 kDa, but we always detected a 46-50 kDa protein by western blot.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Methyltransferase-like protein 21D; Protein N-lysine methyltransferase METTL21D; Valosin-containing protein lysine methyltransferase; VCP lysine methyltransferase; VCP-KMT
基因别名: C14orf138; METTL21D; VCPKMT
Entrez Gene ID: (Human) 79609