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Invitrogen
VGAT Polyclonal Antibody
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Product Details
PA1-4701
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Mouse,
Rat,
Xenopus
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the N-terminal region of rat SLC32A1 conjugated to KLH
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, canine and non-human primate based on 100% sequence homology.
In Western blot, this antibody is specific for the ~53 kDa VGAT protein.
Target Information
The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles (McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GABA and glycine transporter; GVAT; mVGAT; mVIAAT; rat UNC-47 homolog; rGVAT; RUNC-47; solute carrier family 32 (GABA vesicular transporter), member 1; Solute carrier family 32 member 1; vasicular inhibitory amino acid transporter 10D; Vesicular GABA and glycine transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter
Gene Aliases: R75019; Slc32a1; VGAT; Viaat
UniProt ID: (Rat) O35458, (Mouse) O35633
Entrez Gene ID: (Chicken) 419167, (Rat) 83612, (Mouse) 22348
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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