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Abnova
VIL1 Monoclonal Antibody (2F10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00007429-M26
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2F10
抗原
VIL1 (AAH17303, 1 a.a. approximately 421 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.8 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MTKLSAQVKG SLNITTPGLQ IWRIEAMQMV PVPSSTFGSF FDGDCYIILA IHKTASSLSY DIHYWIGQDS SLDEQGAAAI YTTQMDDFLK GRAVQHREVQ GNESEAFRGY FKQGLVIRKG GVASGMKHVE TNSYDVQRLL HVKGKRNVVA GEVEMSWKSF NRGDVFLLDL GKLIIQWNGP ESTRMERLRG MTLAKEIRDQ ERGGRTYVGV VDGENELASP KLMEVMNHVL GKRRELKAAV PDTVVEPALK AALKLYHVSD SEGNLVVREV ATRPLTQDLL SHEDCYILDQ GGLKIYVWKG KKANEQEKKG AMSHALNFIK AKQYPPSTQV EVQNDGAESA VFQQLFQKWT ASNRTSGLGK THTVGSVGEG QAGAVREPGS RSWARRATWS TTHPPSLTCI FNEDFYAGSG LVLADGDVDK L
靶标信息
Villin is part of cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border. It can interact with actin in a Ca2+ and phosphoinositide-regulated manner. Villin is a very specific marker for adenocarcinomas of the gastrointestinal tract and the pancreas. It is also expressed in some Merkel cell tumor and adenocarcinoma of the lung, prostate, ovarian and kidney.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OTTHUMP00000207159; unnamed protein product
基因别名: D2S1471; VIL
UniProt ID: (Human) P09327
Entrez Gene ID: (Human) 7429
intestinal D-glucose absorption
cytoskeleton organization
actin filament organization
epidermal growth factor receptor signaling pathway
actin polymerization or depolymerization
regulation of cell shape
response to bacterium
positive regulation of epithelial cell migration
actin filament polymerization
actin filament depolymerization
positive regulation of cell migration
positive regulation of actin filament depolymerization
epithelial cell differentiation
positive regulation of actin filament bundle assembly
regulation of microvillus length
cellular response to hepatocyte growth factor stimulus
positive regulation of multicellular organism growth
positive regulation of cellular component biogenesis
actin filament severing
barbed-end actin filament capping
regulation of actin nucleation
actin filament capping
cytoplasmic actin-based contraction involved in cell motility
regulation of wound healing
protein-containing complex assembly
cellular response to epidermal growth factor stimulus
positive regulation of lamellipodium organization
terminal web assembly
positive regulation of protein localization to plasma membrane
regulation of lamellipodium morphogenesis
positive regulation of lamellipodium morphogenesis
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