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Invitrogen
VLDLR Polyclonal Antibody
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VLDLR Antibody (PA5-47281) in IHC (F)
Immunohistochemical analysis of VLDLR in perfusion fixed frozen sections of mouse kidney. Samples were incubated with VLDLR polyclonal antibody (Product # PA5-47281) using a dilution of 3 µg/mL for 1 hour at room temperature followed by Anti-Goat IgG VisUCyte™ HRP Polymer Antibody. Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell membra... View More
产品信息
PA5-47281
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse VLDL R Thr25-Ala798
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ35024; Very low-density lipoprotein receptor; VLDL receptor; VLDL-R
基因别名: AA408956; AI451093; AW047288; Vldlr
UniProt ID: (Mouse) P98156
Entrez Gene ID: (Mouse) 22359
negative regulation of transcription from RNA polymerase II promoter
lipid metabolic process
transport
lipid transport
endocytosis
receptor-mediated endocytosis
steroid metabolic process
cholesterol metabolic process
glycoprotein transport
very-low-density lipoprotein particle clearance
reelin-mediated signaling pathway
positive regulation of protein kinase activity
cellular response to hypoxia
positive regulation of dendrite development
