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Invitrogen
VPARP Monoclonal Antibody (P193-4)
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产品信息
MA1-35746
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Arthropod
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
P193-4
抗原
VPARP aa 408-611
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.25 mg/mL
规格
250 µg
纯化类型
purified
保存液
PBS with 1% BSA
内含物
0.1% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
p193-4 reacts with an internal epitope (amino acids 491-494, HPGE) of the minor vault protein (p193 or VPARP), which is overexpressed in various human non-P-glycoprotein MDR tumor cell lines, accordingly to an increase in the number of vault particles. p193-4 was raised against an E. coli lysate transformed with the pET28a(+) expression vector containing amino acids 408-611 of the p193 cDNA.
靶标信息
This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 193 kDa vault protein; ADP-ribosyltransferase diphtheria toxin-like 4; ARTD4; PARP-4; PARP-related/IalphaI-related H5/proline-rich; PH5P; Poly [ADP-ribose] polymerase 4; Protein mono-ADP-ribosyltransferase PARP4; Vault poly(ADP-ribose) polymerase; VPARP
基因别名: ADPRTL1; KIAA0177; PARP4; PARPL
Entrez Gene ID: (Human) 143
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