Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
VPS11 Recombinant Rabbit Monoclonal Antibody (24GB5260)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 3
VPS11 Antibody (MA5-57317) in ICC/IF
Immunocytochemical staining of VPS11 in HepG2 cells using VPS11 Recombinant Monoclonal Antibody (Product # MA5-57317) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; VPS11 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar: 20 μm.
产品信息
MA5-57317
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
24GB5260
抗原
A synthesized peptide derived from human VPS11 (aa 10-44)
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: hVPS11; RING finger protein 108; vacuolar protein sorting 11 homolog; Vacuolar protein sorting-associated protein 11 homolog; VPS11 CORVET/HOPS core subunit
基因别名: 1200011A11Rik; END1; HLD12; hVPS11; PEP5; PP3476; RNF108; VPS11
UniProt ID: (Human) Q9H270, (Mouse) Q91W86
Entrez Gene ID: (Human) 55823, (Mouse) 71732, (Rat) 315600
intracellular protein transport
vesicle docking involved in exocytosis
autophagy
endosome organization
lysosome organization
endosome to lysosome transport
regulation of protein stability
endosomal vesicle fusion
regulation of SNARE complex assembly
regulation of organelle assembly
positive regulation of cellular protein catabolic process
positive regulation of protein targeting to mitochondrion
positive regulation of early endosome to late endosome transport
transport
protein transport
vesicle-mediated transport
toxin transport
