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Invitrogen
VPS8 Monoclonal Antibody (2C8)
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产品信息
MA5-24456
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2C8
抗原
KIAA0804 (NP_001009921, 1329 a.a. ~ 1428 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide Sequence: RITPSQVKMS PSYHQSKGDP TAKKGTSEPV LDPQQIQAFD QLCRLYRGSS RLALLTELSQ NRSSESYRPF SGSQSAPAFN SIFQNENFQL QLIPPPVTED
靶标信息
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predominantly in APPL1-containing endosomes (PubMed:25266290). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: vacuolar protein sorting 8 homolog; Vacuolar protein sorting-associated protein 8 homolog; VPS8 CORVET complex subunit
基因别名: KIAA0804; VPS8
UniProt ID: (Human) Q8N3P4
Entrez Gene ID: (Human) 23355
