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Invitrogen
Villin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5151055
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment of Human Villin (Product # RP-88680).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Highest antigen sequence identity to the following orthologs: Mouse- 85%, Rat- 86%.
Sequence of this protein is as follows: NGPESTRMER LRGMTLAKEI RDQERGGRTY VGVVDGENEL ASPKLMEVMN HVLGKRRELK AAVPDTVVEP ALKAALKLYH VSDSEGNLVV REVATRPLTQ DLLSHE
Target Information
Villin is part of cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border. It can interact with actin in a Ca2+ and phosphoinositide-regulated manner. Villin is a very specific marker for adenocarcinomas of the gastrointestinal tract and the pancreas. It is also expressed in some Merkel cell tumor and adenocarcinoma of the lung, prostate, ovarian and kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000207159; unnamed protein product; Villin-1
Gene Aliases: D2S1471; VIL; VIL1
UniProt ID: (Human) P09327
Entrez Gene ID: (Human) 7429
intestinal D-glucose absorption
apoptotic process
cytoskeleton organization
actin filament organization
epidermal growth factor receptor signaling pathway
actin polymerization or depolymerization
regulation of cell shape
response to bacterium
positive regulation of epithelial cell migration
actin filament polymerization
actin filament depolymerization
positive regulation of cell migration
positive regulation of actin filament depolymerization
epithelial cell differentiation
positive regulation of actin filament bundle assembly
regulation of microvillus length
cellular response to hepatocyte growth factor stimulus
positive regulation of multicellular organism growth
positive regulation of cellular component biogenesis
actin filament severing
barbed-end actin filament capping
regulation of actin nucleation
actin filament capping
cytoplasmic actin-based contraction involved in cell motility
regulation of wound healing
protein-containing complex assembly
cellular response to epidermal growth factor stimulus
positive regulation of lamellipodium organization
terminal web assembly
positive regulation of protein localization to plasma membrane
regulation of lamellipodium morphogenesis
positive regulation of lamellipodium morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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