NeoBiotechnologies

Vimentin (Mesenchymal Cell Marker) Monoclonal Antibody (VM452)

Name: Vimentin (Mesenchymal Cell Marker) Monoclonal Antibody (VM452)
Brand: NeoBiotechnologies
SKU: 7431-MSM1-P1ABX

查看其他109个Vimentin抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (6)

Vimentin (Mesenchymal Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 6

Vimentin (Mesenchymal Cell Marker) Antibody (7431-MSM1-P1ABX) in IHC (P)

Formalin-fixed, paraffin-embedded human Melanoma stained with Vimentin Mouse Monoclonal Antibody (VM452).

Vimentin (Mesenchymal Cell Marker) Antibody in Western Blot (WB)

Vimentin (Mesenchymal Cell Marker) Antibody in Flow Cytometry (Flow)

Vimentin (Mesenchymal Cell Marker) Antibody in Peptide array (ARRAY)

Vimentin (Mesenchymal Cell Marker) Antibody in SDS-PAGE (SDS-PAGE)

Product Image Gallery

Immunogen image

Immunogen Image Vimentin (Mesenchymal Cell Marker) Monoclonal Antibody (VM452)

产品信息

7431-MSM1-P1ABX

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

免疫组化（石蜡） (IHC (P))

Assay-dependent

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1-2 µg/mL

流式细胞分析 (Flow)

1-2 µg/10^6 cells

肽阵列 (Array)

Assay-dependent

产品规格

种属反应

Bovine, Dog, Chicken, Cat, Goat, Human, Pig

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

VM452

抗原

Recombinant full-length human vimentin protein

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Does not react with Mouse or Rat

靶标信息

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。