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Invitrogen
Viral MCK-2 Polyclonal Antibody
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产品信息
PA5-149436
产品规格
种属反应
Virus
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant viral MCK-2
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
MCK-2, also known as Murine Cytomegalovirus Chemokine 2, is a gene encoded by murine cytomegalovirus (MCMV), a model organism used to study cytomegalovirus infections in humans. MCK-2 is a viral chemokine that plays a pivotal role in modulating the host's immune response and facilitating viral dissemination. This chemokine mimics host chemokines by binding to chemokine receptors on immune cells, particularly monocytes and macrophages, and directing their migration to sites of infection. By attracting these cells, MCK-2 helps create an environment conducive to viral replication and spread. Additionally, MCK-2 can interfere with normal immune signaling, aiding the virus in evading immune detection and establishing persistent infection. Understanding the function and mechanisms of MCK-2 is crucial for developing antiviral therapies and improving strategies to manage cytomegalovirus-related diseases. Research into MCK-2 provides valuable insights into viral immune evasion tactics and the complex interactions between viruses and the host immune system, offering potential targets for therapeutic intervention.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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