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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TLLSSKTADV TKVWGMGLNK DSQLGFHRSR KDKTRGYEYV LEPSPVSLPL DRPQETRVLQ VSCGRAHSLV LTDREGVFSM GNNSYGQCGR KVVEN
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion. Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RCC1-like protein; Williams-Beuren syndrome chromosomal region 16 protein; Williams-Beuren syndrome chromosome region 16
基因别名: WBSCR16
UniProt ID: (Human) Q96I51
Entrez Gene ID: (Human) 81554