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Positive test controls include: LO2, U-251MG, A-431, HeLa, Jurkat. The target is usually found in the following locations: Nucleus, nucleoplasm.
Immunogen sequence: EEEEEEDFRK KLNAGYSNTA TEWSQPRFRN QVEEDAEDSG EADDEEKPEI HKPGQNSFSK STNSSDVSAK SGAVTFSSQG RVNPFKVSAS SKEPAMSMNS ARSTNILDNM GKSSKKSTAL SRTTNNEKSP IIKPLIPKPK PKQASAASYF QKRNSQTNKT EEVKEENLKN VLSETPAICP PQNTENQRPK TGFQMWLEEN RSNILSDNPD FSDEADIIKE GMIRFRVLST EERKVWANKA KGETASEGTE AKKRKRVVDE SDETENQEEK AKENLNLSKK QKPLDFSTNQ KLSAFAFKQE
The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Acidic nucleoplasmic DNA-binding protein 1; And-1; CTF4, chromosome transmission fidelity factor 4 homolog; WD repeat and HMG-box DNA-binding protein 1
基因别名: AND-1; AND1; CHTF4; CTF4; WDHD1
UniProt ID: (Human) O75717
Entrez Gene ID: (Human) 11169, (Rat) 305827