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Abnova
WDR4 Monoclonal Antibody (1F9)
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产品信息
H00010785-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1F9
抗原
WDR4 (AAH01074, 1 a.a. approximately 266 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MLLDVAVSPD DRFILTADRD EKIRVSWAAA PHSIESFCLG HTEFVSRISV VPTQPGLLLS SSGDGTLRLW EYRSGRQLHC CHLASLQELV DPQAPQKFAA SRIAFWCQEN CVALLCDGTS VVYIFQLDAR RQQLVYRQQL AFQHQVWDVA FEETQGLWVL QDCQEAPLVL YRPVGDQWQS VPESTVLKKV SGVLRGNWAM LEGSAGADAS FSSLYKATFD NVTSYLKKKE ERLQQQLEKK QRRRSPPPGP DGHAKKMRPG EATLSC
靶标信息
Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hWH; Protein Wuho homolog; TRM82 tRNA methyltransferase 82 homolog; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat-containing protein 4; WDR4
基因别名: TRM82; TRMT82; WDR4
UniProt ID: (Human) B4DNQ7
Entrez Gene ID: (Human) 10785
