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Invitrogen
WDR4 Recombinant Rabbit Monoclonal Antibody (5R7B6)
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WDR4 Antibody (MA5-37987) in IHC (P)
Immunohistochemistry analysis of WDR4 in paraffin-embedded human colon carcinoma. Samples were incubated with WDR4 Monoclonal antibody (Product # MA5-37987) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
产品信息
MA5-37987
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5R7B6
抗原
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human WDR4 (P57081)
偶联物
形式
Liquid
浓度
0.88 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: HeLa, HepG2, A-549, Mouse lung, Mouse spleen, Mouse kidney, Rat kidney
Immunogen sequence: AFWCQENCVA LLCDGTPVVY IFQLDARRQQ LVYRQQLAFQ HQVWDVAFEE TQGLWVLQDC QEAPLVLYRP VGDQWQSVPE STVLKKVSGV LRGNWAMLEG S
靶标信息
Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hWH; mWH; Protein Wuho homolog; TRM82 tRNA methyltransferase 82 homolog; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat-containing protein 4; WD40 repeat protein 4; WDR4
基因别名: AI415180; AI448349; D530049K22Rik; TRM82; TRMT82; WDR4
UniProt ID: (Human) B4DNQ7, (Mouse) Q9EP82
Entrez Gene ID: (Human) 10785, (Mouse) 57773, (Rat) 690032
