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Fabgennix
WDR5 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
WDR5-101AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Dog,
Chicken,
Human,
Mouse,
Non-human primate,
Plant,
Pig,
Rat,
Xenopus,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide:DVKTGKCLKTLPAHSDPVcorresponding to amino acids 157-174 of Human WDR5 protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP-2-induced gene 3 kb; BMP2-induced 3-kb gene protein; cilia and flagella associated protein 89; SWD3, Set1c WD40 repeat protein, homolog; unnamed protein product; WD repeat domain 5; WD repeat-containing protein 5-like; WD repeat-containing protein BIG-3
基因别名: 2410008O07Rik; Big; BIG-3; BIG3; CFAP89; SWD3; WDR5; wu:fk47f04; zgc:56591; zgc:76895
UniProt ID: (Bovine) Q2KIG2, (Human) P61964, (Rat) Q498M4, (Mouse) P61965
Entrez Gene ID: (Bovine) 100125836, (Human) 11091, (Pig) 100156729, (Dog) 608113, (Chicken) 417144, (Rat) 362093, (Mouse) 140858, (Zebrafish) 406372
methylated histone binding
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
histone acetyltransferase activity (H4-K16 specific)
protein binding
histone methyltransferase activity (H3-K4 specific)
histone H3Q5ser reader activity
histone H3K4me1 reader activity
histone reader activity
histone binding
histone H4-K5 acetylation
histone H4-K8 acetylation
histone H4-K16 acetylation
histone H3-K4 methylation
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
peptidyl-lysine methylation
neuron projection development
positive regulation of gluconeogenesis
positive regulation of gene expression, epigenetic
regulation of embryonic development
regulation of cell division
regulation of cell cycle
regulation of tubulin deacetylation
positive regulation of transcription, DNA-templated
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