Invitrogen

WDR65 Polyclonal Antibody

Name: WDR65 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-51738

高级验证

查看其他3个WDR65抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (6)
高级验证 (2)

WDR65 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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WDR65 Antibody (PA5-51738) in IHC (P)

Immunohistochemical analysis of WDR65 in human prostate using WDR65 Polyclonal Antibody (Product # PA5-51738) shows no positivity in glandular cells as expected.

WDR65 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

WDR65 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of WDR65 demonstrates antibody specificity. Immunohistochemical analysis of WDR65 using anti-WDR65 Polyclonal Antibody (Product # PA5-51738), shows significant staining of WDR65 in human fallopian tube and shows minimal or weak staining in human prostate tissues. The relative expression levels of WDR65 within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image WDR65 Polyclonal Antibody

产品信息

PA5-51738

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human WDR65. Recombinant protein control fragment (Product #RP-102002).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2649606

产品详细信息

Immunogen sequence: PESNLVYWLW EKQKVMAIVR IDTQNNPVYQ VSFSPQDNTQ VCVTGNGMFK LLRFAEGTLK QTSFQRGEPQ NYLAHTWVAD DKIVVGTDTG KLFLFESGDQ RWETSIMVKE PTNGSKSLDV IQESESLIEF PPVSSPLP

Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 21%.

靶标信息

The WDR65 gene, which stands for WD Repeat Domain 65, encodes a protein characterized by the presence of WD repeat domains that facilitate protein-protein interactions. This gene is implicated in the assembly of a subset of inner arm dyneins, critical for ciliary motility and axonemal structure. Mutations in WDR65 have been associated with diseases such as Van der Woude syndrome (VWS) and related craniofacial disorders, highlighting its role in developmental processes. Specifically, a missense mutation in WDR65 was identified as a potential cause of VWS, suggesting that WDR65 is a target for regulatory factors like IRF6.

仅用于科研。不用于诊断过程。未经明确授权不得转售。