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Invitrogen
WDR7 Polyclonal Antibody
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WDR7 Antibody (PA5-144042) in IHC (P)
Immunohistochemistry analysis of WDR7 in paraffin-embedded section of mouse brain tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with WDR7 Polyclonal antibody (Product # PA5-144042) using a dilution of 2 μg/mL overnight at 4°C. Peroxidase Conjugated Goat Anti-rabbit IgG was ... View More
产品信息
PA5-144042
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human WDR7 recombinant protein (Position: Q258-Q1292).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human Daudi whole cell, human MOLT-4 whole cell, human HEL whole cell, rat brain tissue, mouse brain tissue. IHC: mouse brain tissue, rat brain tissue. Flow: U20S cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependent exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Rabconnectin-3 beta; rabconnectin-3beta; TGF-beta resistance associated; TGF-beta resistance-associated protein TRAG; WD repeat-containing protein 7
基因别名: AI462727; KIAA0541; mKIAA0541; TRAG; Wd7; WDR7
UniProt ID: (Human) Q9Y4E6, (Mouse) Q920I9, (Rat) Q9ERH3
Entrez Gene ID: (Human) 23335, (Mouse) 104082, (Rat) 66031
