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Immunogen sequence: GSFDNSSLCS GGGDKAVVLW DVASGQVVRK FRGHAGKVNT VQFNEEATVI LSGSIDSSIR CWDCRSRRPE PVQTLDEARD GVSSVKVSDH EIL
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
MORG1 is a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MAPK organizer 1; MGC4238; Mitogen-activated protein kinase organizer 1; WD repeat domain-containing protein 83
基因别名: MORG1; WDR83
UniProt ID: (Human) Q9BRX9
Entrez Gene ID: (Human) 84292