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Invitrogen
WEE2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-140078
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.3 mg/mL
规格
30 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: DIDKELRQKL NFSYCEETEI EGQKKVEESR EASSQTPEKG EVQDSEAKGT PPWTPLSNVH ELDTSSEKDK ESPDQILRTP VSHPLKC
Highest antigen sequence indentity to the following orthologs: Rat - 41%, Mouse - 43%.
靶标信息
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300). Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: WEE1 homolog 2; Wee1-like protein kinase 1B; Wee1-like protein kinase 2; Wee1B kinase
基因别名: OOMD5; OZEMA5; WEE1B; WEE2
UniProt ID: (Human) P0C1S8
Entrez Gene ID: (Human) 494551
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