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Invitrogen
WNT8B Polyclonal Antibody
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产品信息
PA5-33117
产品规格
种属反应
Bat,
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from internal region of human WNT8B.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig (100%); Opossum, Platypus (94%); Marmoset (88%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein Wnt-8b; wingless related MMTV integration site 8b; wingless-type MMTV integration site family member 8B; wingless-type MMTV integration site family, member 8B; WNT 8b
基因别名: I79_016390; WNT8B
UniProt ID: (Human) Q93098, (Mouse) Q9WUD6
signal transduction
gastrulation
nervous system development
Wnt signaling pathway
neuron differentiation
response to estradiol
response to retinoic acid
cell fate commitment
determination of dorsal identity
cellular response to retinoic acid
beta-catenin destruction complex disassembly
cell-cell signaling
multicellular organism development
organ morphogenesis
positive regulation of gene expression
negative regulation of gene expression
biological_process
