Invitrogen

XLF Polyclonal Antibody

Name: XLF Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-96310
Availability: InStock

1个已发表图片

2 篇参考文献

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说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

已发表图片 (1)

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XLF Antibody (PA5-96310) in WB

Nature communications 2024 - Generation and validation of HaloTagged core NHEJ proteins in U20S cells. A Graphical depiction of the long-range XLF-mediated NHEJ synaptic complex and HaloTag (based on PDB: 7NFC and 6U32) , . B Western blots of U2OS cells expressing HaloTagged NHEJ factors and parental U2OS cells probed with antibodies against Ku70 (top), XRCC4 (middle), and XLF (bottom). C Representative images of 20 living cells expres... View More

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image XLF Polyclonal Antibody

产品信息

PA5-96310

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200-1:2,000

查看1篇已发表文章 1篇已发表文章

流式细胞分析 (Flow)

查看1篇已发表文章 1篇已发表文章

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein (or fragment)

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.49 mg/mL

49 µg

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2808112

产品详细信息

Immunogen sequence: MEELEQGLLM QPWAWLQLAE NSLLAKVFIT KQGYALLVSD LQQVWHEQVD TSVVSQRAKE LNKRLTAPPA AFLCHLDNLL RPLLKDAAHP SEATFSCDCV ADALILRVRS ELSGLPFYWN FHCMLASPSL VSQHLIRPLM GMSLALQCQV RELATLLHMK DLEIQDYQES GATLIRDRLK TEPFEENSFL EQFMIEKLPE ACSIGDGKPF VMNLQDLYMA VTTQEVQVGQ KHQGAGDPHT SNSASLQGID SQCVNQPEQL VSSAPTLSAP EKESTGTSGP LQRPQLSKVK RKKPRGLFS; Positive Samples: Hela, Jurkat; Cellular Location: Nucleus

靶标信息

Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.

仅用于科研。不用于诊断过程。未经明确授权不得转售。