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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 57%, Rat- 67%.
Sequence of this protein is as follows: FLEQFMIEKL PEACSIGDGK PFVMNLQDLY MAVTTQEVQV GQKHQGAGDP HTSNSASLQG IDSQCVNQPE QLVSSA
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ12610; Non-homologous end-joining factor 1; Protein cernunnos; XRCC4-like factor
基因别名: NHEJ1; XLF
Entrez Gene ID: (Human) 79840