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PA1-41633 detects Exportin-4 in chicken, chimpanzee, rhesus monkey, canine, human, rat and mouse samples.
This antibody is predicted to react with bovine, xenopus, and zebrafish based on sequence homology.
Suggested positive control: Jurkat whole cell lysate.
Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-4 is a novel mammalian member of this family. It is a RanGTP-binding protein consisting of N-terminal RanGTP-binding motif. It functions as a nuclear export receptor for eIF-5A and also might function as an export adapter in RNA export. It is also involved in nuclear export of Smad3 and regulation of Smad signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Exp4; Exportin-4; FLJ13046
基因别名: B430309A01Rik; exp4; exportin-4; KIAA1721; mKIAA1721; RCJMB04_1f17; XPO4
UniProt ID: (Chicken) Q5ZMR9, (Human) Q9C0E2, (Mouse) Q9ESJ0
Entrez Gene ID: (Chicken) 428081, (Human) 64328, (Dog) 477344, (Mouse) 57258, (Rat) 290280
分子生物学功能: transporter