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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: CEDCNGNVSG GFDASTSQIV LCQNNIHNQA HMNRVVTHEL IHAFDHCRAH VDWFTNIRHL ACSEVRAANL SGDCSLVNEI
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 86%.
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ku70-binding protein 3; Mitochondrial inner membrane protease ATP23 homolog; XRCC6-binding protein 1
基因别名: ATP23; KUB3; XRCC6BP1
Entrez Gene ID: (Human) 91419