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Invitrogen
Yellow Fever Virus NS4B (strain 17D vaccine) Recombinant Rabbit Monoclonal Antibody (HL2449)
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Yellow Fever Virus NS4B (strain 17D vaccine) Antibody (MA5-56926) in ICC/IF
Immunocytochemistry analysis of Yellow Fever Virus NS4B (strain 17D vaccine) using Yellow Fever Virus NS4B (strain 17D vaccine) Recombinant Monoclonal Antibody (Product # MA5-56926) in Mock and transfected 293T cells fixed in 4% paraformaldehyde at RT for 15 min. Yellow Fever Virus NS4B (strain 17D vaccine) antibody diluted at 1:500. Blue: Fluoroshield with DAPI.
产品信息
MA5-56926
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2449
抗原
Full length Yellow Fever virus NS4B Protein.(strain 17D vaccine)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
The NS4B protein of the Yellow Fever Virus (YFV) is a non-structural protein that plays a crucial role in the virus's replication process. As part of the viral replication complex, NS4B is involved in the formation of membrane-associated replication compartments within the host cell, which are essential for efficient viral RNA synthesis. This protein also interacts with other non-structural proteins and host factors to modulate the host's immune response, aiding in viral evasion of immune detection. Due to its integral role in the replication and immune modulation, NS4B is considered a significant target for antiviral drug development. Inhibiting NS4B function can potentially disrupt the viral replication cycle, thereby reducing viral load and disease severity. Current research is focused on understanding the precise mechanisms of NS4B's interactions and functions, which could lead to the development of novel therapeutic interventions aimed at combating yellow fever and other flavivirus infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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