Search
Invitrogen
ZBTB16 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100891
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ZBTB16(Accession Q05516), corresponding to amino acid residues I158-T208.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ZBTB16.
靶标信息
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Green's luxoid; Kruppel-like; PLZF; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; unnamed protein product; zinc finger and BTB domain containing 16 protein; zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF
基因别名: lu; Lx; PLZF; Zfp145; ZNF145
UniProt ID: (Human) Q05516
Entrez Gene ID: (Human) 7704, (Rat) 353227, (Mouse) 235320
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription corepressor binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
protein binding
protein domain specific binding
type 2 angiotensin receptor binding
identical protein binding
protein homodimerization activity
RNA polymerase II transcription factor activity, sequence-specific DNA binding
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
mesonephros development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
central nervous system development
negative regulation of cell proliferation
embryonic pattern specification
anterior/posterior pattern specification
regulation of gene expression
hemopoiesis
positive regulation of chondrocyte differentiation
protein localization to nucleus
embryonic hindlimb morphogenesis
forelimb morphogenesis
hindlimb morphogenesis
embryonic digit morphogenesis
positive regulation of apoptotic process
ossification involved in bone maturation
regulation of cell differentiation
positive regulation of fat cell differentiation
negative regulation of myeloid cell differentiation
positive regulation of ossification
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
male germ-line stem cell asymmetric division
positive regulation of NK T cell differentiation
cartilage development
positive regulation of multicellular organismal process
positive regulation of cartilage development
regulation of multicellular organismal development
tolerance induction in gut-associated lymphoid tissue
apoptotic process
protein ubiquitination
myeloid cell differentiation
regulatory T cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
