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Invitrogen
ZBTB49 Recombinant Mouse Monoclonal Antibody (K29068_18A12)
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ZBTB49 Antibody (MA564437) in IHC (P)
Immunohistochemistry (Paraffin) analysis of ZBTB49 in formalin-fixed paraffin-embedded brain tissue. Samples were incubated with ZBTB49 recombinant monoclonal (Product # MA564437) using a dilution of 7 µg/mL at room temperature for 1 hr followed by Poly-peroxidase conjugated goat anti-mouse IgG. Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenou... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA564437
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K29068_18A12
抗原
Recombinant human ZBTB49 (aa 231-410).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS with 0.5% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PSQERVVEQP FAFSTSTDLT TVESQPCAVS HSECILESPE HLPSNFLAQP VNDSAPHPES DATCQQPVKQ MRLKKAIHLK KLNFLKSQKY AEQVSEPKSD DGLTKRLESA SKNTLEKASS QSAEEKESEE VVSCENFNCI SETERPEDPA ALEDQSQTLQ SQRQYACELC GKPFKHPSNL
Highest antigen sequence identity to the following orthologs: Mouse - 57%, Pig - 64%, Cynomolgus monkey - 95%.
靶标信息
Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: unnamed protein product; zinc finger protein 509
基因别名: ZNF509
UniProt ID: (Human) Q6ZSB9
Entrez Gene ID: (Human) 166793
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription coactivator binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
sequence-specific DNA binding
DNA-binding transcription factor binding
negative regulation of transcription from RNA polymerase II promoter
regulation of cytokine production
regulation of immune system process
regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of cell cycle
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