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Invitrogen
ZBTB8A Polyclonal Antibody
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ZBTB8A Antibody (PA5-116783) in WB
Western blot analysis of ZBTB8A in extracts of various cell lines. Samples were incubated with ZBTB8A Polyclonal antibody (Product # PA5-116783) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-116783
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human ZBTB8A (NP_001035531)
偶联物
形式
Liquid
浓度
0.82 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: U-87MG, PC-3, HeLa, Mouse lung, Mouse brain, Rat heart
Immunogen sequence: HEPRKESIKK TKHLRLSQPS EVTHYKSSKR EVRTSDSSSH VSQSEEQAQI DAEMDSTPVG YQYGQGSDVT SKSFPDDLPR MRFKCPYCTH VVKRKADLKR HLRCHTGERP YPCQACGKRF SRLDHLSSHF RTIHQACKLI CRKCKRHVTD LTGQVVQEGT RRYRLCNECL AEFGIDSLPI DLEAEQHLMS PSDGDKDSRW H
靶标信息
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BOZ-F1; BTB/POZ and zinc-finger domain-containing factor; BTB/POZ and zinc-finger domains factor on chromosome 1; zinc finger and BTB domain containing 8; Zinc finger and BTB domain-containing protein 8A
基因别名: 2410081M15Rik; AI480941; BOZF1; ZBTB8; ZBTB8A; ZNF916A
UniProt ID: (Human) Q96BR9, (Mouse) Q9CWH1
Entrez Gene ID: (Human) 653121, (Rat) 313049, (Mouse) 73680
