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Immunogen sequence: GYDREDVLRV LGKLGEGALV NDVLQELIRT GSRPGALEHP AAPRLVPRGS CGVPDSAQRG PGTALEEDFR TLA
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 64%.
ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MCP-induced protein 4; p34; Probable ribonuclease ZC3H12D; RP1-281H8.5; Transformed follicular lymphoma; tumor suppressor TFL; Zinc finger CCCH domain-containing protein 12D
基因别名: C6orf95; dJ281H8.1; MCPIP4; p34; TFL; ZC3H12D
UniProt ID: (Human) B7WNU7
Entrez Gene ID: (Human) 340152
分子生物学功能: endoribonuclease