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Invitrogen
ZDHHC18 Polyclonal Antibody
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ZDHHC18 Antibody (PA5-116614) in IHC (P)
Immunohistochemistry analysis of ZDHHC18 in paraffin-embedded human lung cancer. Samples were incubated with ZDHHC18 Polyclonal antibody (Product # PA5-116614) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-116614
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 301-388 of human ZDHHC18 (NP_1156591)
偶联物
形式
Liquid
浓度
1.399 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Raji, HeLa, Mouse brain, Rat brain
Immunogen sequence: YLVASNLTTN EDIKGSWSSK RGGEASVNPY SHKSIITNCC AVLCGPLPPS LIDRRGFVQS DTVLPSPIRS DEPACRAKPD ASMVGGHP
靶标信息
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DHHC domain-containing cysteine-rich protein 18; DHHC-18; membrane-associated DHHC18 zinc finger protein; Palmitoyltransferase ZDHHC18; Zinc finger DHHC domain-containing protein 18; zinc finger, DHHC domain containing 18; zinc finger, DHHC-type containing 18
基因别名: DHHC-18; DHHC18; ZDHHC18
UniProt ID: (Human) Q9NUE0, (Mouse) Q5Y5T2, (Rat) Q2TGJ1
Entrez Gene ID: (Human) 84243, (Mouse) 503610, (Rat) 362613
