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Invitrogen
ZDHHC20 Polyclonal Antibody
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ZDHHC20 Antibody (PA5-116796) in WB
Western blot analysis of ZDHHC20 in extracts of various cell lines. Samples were incubated with ZDHHC20 Polyclonal antibody (Product # PA5-116796) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
产品信息
PA5-116796
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 270-365 of human ZDHHC20 (NP_0013169881)
偶联物
形式
Liquid
浓度
1.03 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: HeLa, MCF7, SKOV3, A-549, Mouse brain, Mouse lung, Mouse testis, Rat brain, Rat lung
Immunogen sequence: VFGDEKKYWL LPIFSSLGDG CSFPTRLVGM DPEQASVTNQ NEYARSSGSN QPFPIKPLSE SKNRLLDSES QWLENGAEEG IVKSGTNNHV TVAIEN
靶标信息
Catalyzes palmitoylation of Cys residues on target proteins (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245). [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acyltransferase ZDHHC20; DHHC domain-containing cysteine-rich protein 20; DHHC-20; DHHC-containing protein 20; DHHC20; membrane-associated DHHC24 zinc finger protein; Palmitoyltransferase ZDHHC20; probable palmitoyltransferase ZDHHC20; Zinc finger DHHC domain-containing protein 20; zinc finger, DHHC domain containing 20; zinc finger, DHHC-type containing 20
基因别名: 4933421L13Rik; 5033406L14Rik; AI448102; B230110O18Rik; DHHC-20; HK11; RGD1305755; ZDHHC20
UniProt ID: (Human) Q5W0Z9, (Mouse) Q5Y5T1
Entrez Gene ID: (Human) 253832, (Rat) 305923, (Mouse) 75965
